Prednisone and Alcohol: Consequences of the Combination

Prednisone (Prednisone) medicinal salt is directed to treat arthritis, skin conditions, severe allergies, asthma, a blood disorder, and other conditions.

The detailed information related to Prednisone’s experiments, side effects, reviews, questions, interactions, and precautions is as follows:


Prednisone is used to treat, control, prevent, and improve the following diseases, conditions, and symptoms:

  • Arthritis
  • Skin conditions
  • Severe allergies
  • Asthma
  • blood disorder

Prednisone Side Effects

The following is a list of the possible side effects of those medications that include Prednisone (Prednisone). This is not a comprehensive list. These side effects are possible but are not always there. Some side effects can be severe but rare. If you find any of the following side effects, consult your doctor if they do not end.

  • Acne
  • dizziness
  • Face redness
  • Experiencing spinning speed
  • General restlessness
  • Headache
  • Increased hunger
  • Excess sweating
  • Nausea

If you find any side effects that are not listed above, contact your doctor for medical advice. You can also inform your local food and pharmaceutical management officer about the side effects.


Prednisone Precautions

Before using this drug, consult your doctor about your current medicines, indirect products (e.g., vitamins, herbal supplements, etc.), allergens, pre-existing diseases, and current health conditions (e.g., pregnancy, upcoming surgery, etc.); provide information. Some health conditions can make you more susceptible to the side effects of the drug. According to your doctor’s instructions, take medication, or follow the instructions printed on the product. Dosage is based on your condition. If there is no improvement in your state or if your condition worsens, then tell your doctor. Important consulting points have been listed below.

  • Adrenal gland problems
  • high blood pressure
  • Pregnant
  • Pregnancy planning
  • kidney problems
  • Liver problems
  • heart attack
  • Tour
  • Passive hormone
  • diabetes

Interaction with Prednisone

If you consume other medicines or undetermined products simultaneously, Prednisone’s effect (Prednisone) may change. It may increase your risk of side effects or because of this. You should tell your doc about all the medicines, vitamins, and herbal supplements you are using so that your physician can help you avoid the drug’s side effects. Prednisone (Prednisone) can interact with the following medicines and products:

  • Aspirin
  • Birth control pills
  • Carbamazepine
  • Clarithromycin
  • Cyclosporine
  • Ephedrine
  • Estradiol
  • Furosemide
  • Hydrochlorothiazide
  • Ketoconazole

When to use Prednisone

Hypnosis is a taboo for Prednisone (Prednisone). Also, if you have any of the following problems, then Prednisone (Prednisone) should not be taken:

  • Eye irritation
  • Inflammation of the optic nerve
  • Allergic
  • Fungal infection
  • Malaria


prednisone and alcohol

If you combine Prednisolone with the use of alcohol, it does not provoke hazardous conditions. Theoretically, this hormonal drug and ethanol are compatible; that is, they do not encourage the creation of some toxic formations. But doctors noted the following situations if alcohol was used during the treatment:

  • exacerbation of existing chronic pathologies;
  • a significant decrease in the expected effects of treatment.

In this case, doctors, talking about the compatibility of Prednisolone and alcohol, consider the feasibility of this tandem. When long-term therapy is applied (in the treatment of chronic illnesses), and one-time alcohol intake occurs, the patient does not observe any negative consequences. But things will be different in the case of regular consumption of alcohol.

In this case (when combining large and constant doses of alcohol and a hormonal drug) gives a sharply negative effect. It must be borne in mind that Prednisolone affects blood pressure; it increases its performance. With additional exposure to alcohol, this problem only grows.

It should be borne in mind that the treatment with hormonal medicines is based on stopping the pathological manifestations occurring in the body. In this case, the additional effect of ethyl alcohol will only aggravate the manifestation of existing diseases. And the expected impact of treatment will significantly decrease.


In the early stages of intoxication, both the drug and the alcohol affect the central nervous system almost identically. Both substances inhibit the system’s natural reactions, suppress depressive feelings and anxiety, give a sense of euphoria, and a little disoriented in space. In some cases, the opposite effect may occur (depending on tolerance to alcohol and external factors) after an additional portion of alcohol hallucinations are formed and the nervous system’s possible malfunctions. If the concentration of ethyl alcohol in the body is prohibitive – withdrawal syndrome and psychosis develop.

A dangerous combination also affects the state of the cardiovascular system. Among them:

  • narrowing of the blood vessels;
  • increase in the number of heart contractions;
  • blood pressure jumps;
  • malfunction of the heart muscle;
  • blood stasis and blood clot formation;
  • increased risk of exacerbation of chronic diseases.

The negative impact on the digestive system. Synthesis of prostaglandins, which protect the mucous membranes of internal organs, making them vulnerable decreases. Additionally, the secretion of gastric juice increases, leading to the formation of ulcers and erosions. The maximum impact is on the liver, which cannot absorb and alcohol and active medication. Intense stress triggers the process of destruction in all systems and organs, which can lead to death.

What consequences can be expected

The compatibility of alcoholic beverages and the hormone drug Prednisolone is questionable. The exclusion is a one-time use of alcohol in small doses. In this case, such a combination of the therapeutic process does not have a significant negative impact.

But the consequences of such a tandem become different in the case of constant alcohol consumption in excess. In such a situation, alcohol will significantly worsen all the adverse and concomitant effects of Prednisone’s long-term intake. In particular:

  • increased heart rate;
  • risk of developing convulsive states;
  • respiratory depression (it becomes frequent and superficial);
  • increased pressure due to a sharp narrowing of the blood vessels.

Dangerous consequences

Ethanol can provoke the development of puffiness due to the accumulation of intracellular fluid. Whereas Prednisolone actively removes potassium from the body. When combining similar properties in some patients (especially those suffering from heart disease), such a tandem can cause severe problems in the work of the heart and a sharp increase in heartbeat.

Also, the dangerous consequences of this combination may be noted by the work of the digestive system’s brain and organs. In this case, the patient may experience:

  • liver damage;
  • perforation of the stomach;
  • exacerbation of the current disease;
  • violation of brain activity;
  • development of ulcers (gastrointestinal tract and duodenum).

There is also a high risk of a sharp deterioration in the patient’s current condition due to an existing chronic disease complication. Therefore, in most cases, doctors do not recommend against the background of the course of treatment with Prednisone (and it never lasts more than two weeks) to drink alcoholic beverages.

When can I have a drink?

So, against the background of therapy with Prednisolone’s use, doctors do not recommend consuming alcohol. Especially if there is treatment with the help of large doses of hormonal drugs. If there is a long therapeutic course, and a critical solemn event is planned on the nose, then you can take part in the public holiday, but with the following conditions:

  1. Drink low-alcohol in small doses.
  2. Take alcohol only after 4-5 hours since the last drug intake.

A treatment course should be started only after a complete cleansing of the body from ethanol products. This time is calculated individually, considering numerous factors (gender, weight, age, health, type, and strength of alcohol). But even despite the available permits, it will still be safer for the sake of your health during the treatment with Prednisone to forget about the existence of alcoholic beverages.


Combination rules

To take alcohol during treatment with this drug is not recommended, and if the drug is prescribed in a high dose, it is impossible to drink alcohol-containing beverages categorically.

In cases where the drug is taken in long-term courses, in a small dosage, and there is an important event ahead of which you must drink alcohol, you need to try to get over 4 hours after taking medicine.

After alcohol, you can drink medicine only after the complete elimination of ethyl alcohol. The time it takes ethanol to leave the body completely can be calculated using an alcohol calculator.


So is it possible to drink alcohol when taking Prednisolone? Doctors recommend eliminate alcohol during drug treatment, do not combine them in any way. The danger lies in the characteristics of both alcohol and Prednisolone to increase the pressure, to provoke a stomach ulcer.

According to doctors, combining hormone therapy with alcohol is extremely dangerous for health.

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